| Jack Banta | Punter (uncredited) |
| Tommy Bennett | O'Reilly (uncredited) |
| Georgie Billings | Boy Quarterback (uncredited) |
| Wade Boteler | Trainer (uncredited) |
| Egon Brecher | Elder in Norway (uncredited) |
| David Bruce | Reporter When Knute is Ill (uncredited) |
| Cliff Clark | Danny - Post Office Paymaster (uncredited) |
| Richard Clayton | O'Flaherty - a Student (uncredited) |
| Frank Coghlan Jr. | Messenger (uncredited) |
| Joe Cunningham | Reporter on Train (uncredited) |
| Donald Curtis | West Point Football Player (uncredited) |
| Billy Dawson | Knute Rockne Jr. - Age 12 (uncredited) |
| Edgar Dearing | Doc - Knute's Friend at Kansas City Airport (uncredited) |
| Dudley Dickerson | Train Porter (uncredited) |
| Lucile Fairbanks | Telephone Operator (uncredited) |
| James Flavin | Army Assistant Coach (uncredited) |
| Bunky Fleischman | Bill Rockne - Age 5 (uncredited) |
| John Gallaudet | Notre Dame Coach Harper (uncredited) |
| Peter B. Good | Bill 'Billy' Rockne - Age 2 (uncredited) |
| Sol Gorss | Man Wheeling Knute's Wheelchair (uncredited) |
| Jack Grant Jr. | Bill Rockne - Age 14 (uncredited) |
| Billy Gratton | Jackie Rockne - Age 4 (uncredited) |
| Creighton Hale | Callahan's Secretary (uncredited) |
| Harry Harvey Jr. | Boy (uncredited) |
| Michael Harvey | Football Player (uncredited) |
| Harry Hayden | Committee Member (uncredited) |
| Patricia Hayes | Jeannie Rockne - Age 10 (uncredited) |
| George Haywood | Student (uncredited) |
| Oscar 'Dutch' Hendrian | Assistant Coach Hunk Anderson (uncredited) |
| William Hopper | New York Reporter When Knute is Ill (uncredited) |
| George Irving | Doc - a Notre Dame Professor (uncredited) |
| Danny Jackson | Boy (uncredited) |
| Lois James | Bathing Beauty (uncredited) |
| Dickie Jones | Boy Captain (uncredited) |
| Brian Keith | Student at Train Station (uncredited) |
| Owen King | Western Union Clerk in Kansas City (uncredited) |
| Marilyn Kinsley | Bathing Beauty (uncredited) |
| Lois Lindsay | Bathing Beauty (uncredited) |
| Pete Mehringer | Football Player (uncredited) |
| Carlyle Moore Jr. | Player Eating Bonnie's Chicken (uncredited) |
| Paul Panzer | Extra at Train Station (uncredited) |
| Steve Pendleton | Football Player #12 (uncredited) |
| Lee Phelps | Army Coach (uncredited) |
| George Reeves | Distraught Player (uncredited) |
| Sam Rice | Extra at Committee Hearing (uncredited) |
| Ruth Robinson | Molly - Gipp's Mother (uncredited) |
| Jeffrey Sayre | Jeff - Reporter on Train (uncredited) |
| Billy Sheffield | Knute Rockne - Age 4 (uncredited) |
| Edwin Stanley | Committee Member (uncredited) |
| Phil Thorpe | Boy Center (uncredited) |
| Ruth Tobey | Isobel (uncredited) |
| Charles Trowbridge | Professor (uncredited) |
| Frederick Vogeding | Elder in Norway (uncredited) |
| David Wade | Knute Rockne - Age 7 (uncredited) |
| Pierre Watkin | Commissioner at Hearing (uncredited) |
| Garry Watson | Boy (uncredited) |
| Charles Cahill Wilson | Gambler (uncredited) |
| Robert Winkler | Tommy (uncredited) |
| Jack Wise | Football Fan at Game (uncredited) |
| Maris Wrixon | Telephone Operator (uncredited) |
